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Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein

Accumulating evidence suggests an important role for the Disrupted-in-Schizophrenia 1 (DISC1) protein in neurodevelopment and chronic mental illness. In particular, the C-terminal 300 amino acids of DISC1 have been found to mediate important protein-protein interactions and to harbor functionally im...

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Detalles Bibliográficos
Autores principales: Yerabham, Antony S. K., Müller-Schiffmann, Andreas, Ziehm, Tamar, Stadler, Andreas, Köber, Sabrina, Indurkhya, Xela, Marreiros, Rita, Trossbach, Svenja V., Bradshaw, Nicholas J., Prikulis, Ingrid, Willbold, Dieter, Weiergräber, Oliver H., Korth, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764400/
https://www.ncbi.nlm.nih.gov/pubmed/29324815
http://dx.doi.org/10.1371/journal.pone.0191162