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LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition

Leptospirosis is a widespread zoonosis, potentially severe in humans, caused by spirochetal bacteria, Leptospira interrogans (L. interrogans). Host defense mechanisms involved in leptospirosis are poorly understood. Recognition of lipopolysaccharide (LPS) and lipoproteins by Toll-Like Receptors (TLR...

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Detalles Bibliográficos
Autores principales: Ratet, Gwenn, Santecchia, Ignacio, Fanton d’Andon, Martine, Vernel-Pauillac, Frédérique, Wheeler, Richard, Lenormand, Pascal, Fischer, Frédéric, Lechat, Pierre, Haake, David A., Picardeau, Mathieu, Boneca, Ivo G., Werts, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764436/
https://www.ncbi.nlm.nih.gov/pubmed/29211798
http://dx.doi.org/10.1371/journal.ppat.1006725