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Synthesis, characterization and in vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety

The reported toxicities of current antitrypanosomal drugs and the emergence of drug resistant trypanosomes underscore the need for the development of new antitrypanosomal agents. We report herein the synthesis and antitrypanosomal activity of 24 new amide derivatives of 3-aminoquinoline, bearing sub...

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Detalles Bibliográficos
Autores principales: Ugwu, David Izuchukwu, Okoro, Uchechukwu Chris, Mishra, Narendra Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764481/
https://www.ncbi.nlm.nih.gov/pubmed/29324817
http://dx.doi.org/10.1371/journal.pone.0191234