Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Modify Microglial Response and Improve Clinical Outcomes in Experimental Spinal Cord Injury

No current clinical intervention can alter the course of acute spinal cord injury (SCI), or appreciably improve neurological outcome. Mesenchymal stromal cells (MSCs) have been shown to modulate the injury sequelae of SCI largely via paracrine effects, although the mechanisms remain incompletely und...

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Detalles Bibliográficos
Autores principales: Ruppert, Katherine A., Nguyen, Tin T., Prabhakara, Karthik S., Toledano Furman, Naama E., Srivastava, Amit K., Harting, Matthew T., Cox, Charles S., Olson, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764957/
https://www.ncbi.nlm.nih.gov/pubmed/29323194
http://dx.doi.org/10.1038/s41598-017-18867-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764957/
https://www.ncbi.nlm.nih.gov/pubmed/29323194
http://dx.doi.org/10.1038/s41598-017-18867-w

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