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Discovery of Hepatotoxic Equivalent Combinatorial Markers from Dioscorea bulbifera tuber by Fingerprint-Toxicity Relationship Modeling

Due to extremely chemical complexity, identification of potential toxicity-related constituents from an herbal medicine (HM) still remains challenging. Traditional toxicity-guided separation procedure suffers from time- and labor-consumption and neglects the additive effect of multi-components. In t...

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Detalles Bibliográficos
Autores principales: Shi, Wei, Zhang, Cai, Zhao, Dongsheng, Wang, Lingli, Li, Ping, Li, Huijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764974/
https://www.ncbi.nlm.nih.gov/pubmed/29323207
http://dx.doi.org/10.1038/s41598-017-18929-z