Sequential forward and reverse transport of the Na(+) Ca(2+) exchanger generates Ca(2+) oscillations within mitochondria

Mitochondrial Ca(2+) homoeostasis regulates aerobic metabolism and cell survival. Ca(2+) flux into mitochondria is mediated by the mitochondrial calcium uniporter (MCU) channel whereas Ca(2+) export is often through an electrogenic Na(+)–Ca(2+) exchanger. Here, we report remarkable functional versat...

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Detalles Bibliográficos
Autores principales: Samanta, Krishna, Mirams, Gary R., Parekh, Anant B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765001/
https://www.ncbi.nlm.nih.gov/pubmed/29323106
http://dx.doi.org/10.1038/s41467-017-02638-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765001/
https://www.ncbi.nlm.nih.gov/pubmed/29323106
http://dx.doi.org/10.1038/s41467-017-02638-2

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