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Microbial synthesis of a useful optically active (+)-isomer of lactone with bicyclo[4.3.0]nonane structure
Lactone 2a of a bicyclo[4.3.0]nonane structure is a good starting material for synthesis of many attractive compounds. Enantiomerically enriched (−)-(3aR,7aS)-lactone 2a is produced by whole cells of bacteria. In order to examine the impact of the absolute configuration on biological activity we eva...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765023/ https://www.ncbi.nlm.nih.gov/pubmed/29323184 http://dx.doi.org/10.1038/s41598-017-18876-9 |