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Microbial synthesis of a useful optically active (+)-isomer of lactone with bicyclo[4.3.0]nonane structure

Lactone 2a of a bicyclo[4.3.0]nonane structure is a good starting material for synthesis of many attractive compounds. Enantiomerically enriched (−)-(3aR,7aS)-lactone 2a is produced by whole cells of bacteria. In order to examine the impact of the absolute configuration on biological activity we eva...

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Detalles Bibliográficos
Autores principales:	Boratyński, Filip, Janik-Polanowicz, Agata, Szczepańska, Ewa, Olejniczak, Teresa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765023/ https://www.ncbi.nlm.nih.gov/pubmed/29323184 http://dx.doi.org/10.1038/s41598-017-18876-9

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