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Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells

Human mesenchymal stem cells (hMSCs) show promise for bone and cartilage regeneration. Our previous studies demonstrated that hMSCs with periodic mild heating had enhanced osteogenic and chondrogenic differentiation with significantly upregulated heat shock protein 70 (HSP70). However, the role of H...

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Detalles Bibliográficos
Autores principales: Li, Chenghai, Sunderic, Kristifor, Nicoll, Steven B., Wang, Sihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765044/
https://www.ncbi.nlm.nih.gov/pubmed/29323151
http://dx.doi.org/10.1038/s41598-017-18541-1