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Skeletal Characterization of the Fgfr3 Mouse Model of Achondroplasia Using Micro-CT and MRI Volumetric Imaging

Achondroplasia, the most common form of dwarfism, affects more than a quarter million people worldwide and remains an unmet medical need. Achondroplasia is caused by mutations in the fibroblast growth factor receptor 3 (FGFR3) gene which results in over-activation of the receptor, interfering with n...

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Detalles Bibliográficos
Autores principales: Shazeeb, Mohammed Salman, Cox, Megan K., Gupta, Anurag, Tang, Wen, Singh, Kuldeep, Pryce, Cynthia T., Fogle, Robert, Mu, Ying, Weber, William D., Bangari, Dinesh S., Ying, Xiaoyou, Sabbagh, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765052/
https://www.ncbi.nlm.nih.gov/pubmed/29323153
http://dx.doi.org/10.1038/s41598-017-18801-0