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Skeletal Characterization of the Fgfr3 Mouse Model of Achondroplasia Using Micro-CT and MRI Volumetric Imaging
Achondroplasia, the most common form of dwarfism, affects more than a quarter million people worldwide and remains an unmet medical need. Achondroplasia is caused by mutations in the fibroblast growth factor receptor 3 (FGFR3) gene which results in over-activation of the receptor, interfering with n...
Autores principales: | Shazeeb, Mohammed Salman, Cox, Megan K., Gupta, Anurag, Tang, Wen, Singh, Kuldeep, Pryce, Cynthia T., Fogle, Robert, Mu, Ying, Weber, William D., Bangari, Dinesh S., Ying, Xiaoyou, Sabbagh, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765052/ https://www.ncbi.nlm.nih.gov/pubmed/29323153 http://dx.doi.org/10.1038/s41598-017-18801-0 |
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