Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications

Platelet activation triggers thrombus formation in physiological and pathological conditions, such as acute coronary syndromes. Current therapies still fail to prevent thrombotic events in numerous patients, indicating that the mechanisms modulating platelet response during activation need to be cla...

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Detalles Bibliográficos
Autores principales: Nassa, Giovanni, Giurato, Giorgio, Cimmino, Giovanni, Rizzo, Francesca, Ravo, Maria, Salvati, Annamaria, Nyman, Tuula A., Zhu, Yafeng, Vesterlund, Mattias, Lehtiö, Janne, Golino, Paolo, Weisz, Alessandro, Tarallo, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765118/
https://www.ncbi.nlm.nih.gov/pubmed/29323256
http://dx.doi.org/10.1038/s41598-017-18985-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765118/
https://www.ncbi.nlm.nih.gov/pubmed/29323256
http://dx.doi.org/10.1038/s41598-017-18985-5

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