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Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression

BACKGROUND: Metastatic castration-resistant prostate cancer (mCRPC) is one of the main contributors to the death of prostate cancer patients. To date, the detailed molecular mechanisms underlying mCRPC are unclear. Given the crucial role of epithelial–mesenchymal transition (EMT) in cancer metastasi...

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Detalles Bibliográficos
Autores principales: Hu, Jieping, Tian, Jing, Zhu, Shimiao, Sun, Libin, Yu, Jianpeng, Tian, Hao, Dong, Qian, Luo, Qiang, Jiang, Ning, Niu, Yuanjie, Shang, Zhiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765224/
https://www.ncbi.nlm.nih.gov/pubmed/29123266
http://dx.doi.org/10.1038/bjc.2017.372