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Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression
BACKGROUND: Metastatic castration-resistant prostate cancer (mCRPC) is one of the main contributors to the death of prostate cancer patients. To date, the detailed molecular mechanisms underlying mCRPC are unclear. Given the crucial role of epithelial–mesenchymal transition (EMT) in cancer metastasi...
Autores principales: | Hu, Jieping, Tian, Jing, Zhu, Shimiao, Sun, Libin, Yu, Jianpeng, Tian, Hao, Dong, Qian, Luo, Qiang, Jiang, Ning, Niu, Yuanjie, Shang, Zhiqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765224/ https://www.ncbi.nlm.nih.gov/pubmed/29123266 http://dx.doi.org/10.1038/bjc.2017.372 |
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