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Association between SLC19A1 Gene Polymorphism and High Dose Methotrexate Toxicity in Childhood Acute Lymphoblastic Leukaemia and Non Hodgkin Malignant Lymphoma: Introducing a Haplotype based Approach

BACKGROUND: We investigated the clinical relevance of SLC 19A1 genetic variability for high dose methotrexate (HD-MTX) related toxicities in children and adolescents with acute lymphoblastic leukaemia (ALL) and non Hodgkin malignant lymphoma (NHML). PATIENTS AND METHODS: Eighty-eight children and ad...

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Detalles Bibliográficos
Autores principales: Kotnik, Barbara Faganel, Jazbec, Janez, Grabar, Petra Bohanec, Rodriguez-Antona, Cristina, Dolzan, Vita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter Open 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765323/
https://www.ncbi.nlm.nih.gov/pubmed/29333125
http://dx.doi.org/10.1515/raon-2017-0040