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Genome-Wide Mapping of Decay Factor–mRNA Interactions in Yeast Identifies Nutrient-Responsive Transcripts as Targets of the Deadenylase Ccr4

The Ccr4 (carbon catabolite repression 4)-Not complex is a major regulator of stress responses that controls gene expression at multiple levels, from transcription to mRNA decay. Ccr4, a “core” subunit of the complex, is the main cytoplasmic deadenylase in Saccharomyces cerevisiae; however, its mRNA...

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Detalles Bibliográficos
Autores principales: Miller, Jason E., Zhang, Liye, Jiang, Haoyang, Li, Yunfei, Pugh, B. Franklin, Reese, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765359/
https://www.ncbi.nlm.nih.gov/pubmed/29158339
http://dx.doi.org/10.1534/g3.117.300415