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A Single Residue Mutation in the Gα(q) Subunit of the G Protein Complex Causes Blindness in Drosophila

Heterotrimeric G proteins play central roles in many signaling pathways, including the phototransduction cascade in animals. However, the degree of involvement of the G protein subunit Gα(q) is not clear since animals with previously reported strong loss-of-function mutations remain responsive to li...

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Detalles Bibliográficos
Autores principales: Cao, Jinguo, Bollepalli, Murali K., Hu, Yuhui, Zhang, Jin, Li, Qiang, Li, Hongmei, Chang, Hua, Xiao, Feng, Hardie, Roger C., Rong, Yikang S., Hu, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765363/
https://www.ncbi.nlm.nih.gov/pubmed/29158337
http://dx.doi.org/10.1534/g3.117.300340