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A Single Residue Mutation in the Gα(q) Subunit of the G Protein Complex Causes Blindness in Drosophila
Heterotrimeric G proteins play central roles in many signaling pathways, including the phototransduction cascade in animals. However, the degree of involvement of the G protein subunit Gα(q) is not clear since animals with previously reported strong loss-of-function mutations remain responsive to li...
Autores principales: | Cao, Jinguo, Bollepalli, Murali K., Hu, Yuhui, Zhang, Jin, Li, Qiang, Li, Hongmei, Chang, Hua, Xiao, Feng, Hardie, Roger C., Rong, Yikang S., Hu, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765363/ https://www.ncbi.nlm.nih.gov/pubmed/29158337 http://dx.doi.org/10.1534/g3.117.300340 |
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