Generation of T follicular helper cells in vitro: requirement for B‐cell receptor cross‐linking and cognate B‐ and T‐cell interaction

The minimum requirements for in vitro modelling of natural CD4(+) T‐cell differentiation into T follicular helper (Tfh) cells are still under investigation. We co‐cultured wild‐type and T‐cell receptor (TCR) transgenic CD4(+) T cells from naive mice with dendritic cells and B‐cell receptor (BCR) tra...

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Detalles Bibliográficos
Autores principales: Kolenbrander, Anne, Grewe, Bastian, Nemazee, David, Überla, Klaus, Temchura, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765376/
https://www.ncbi.nlm.nih.gov/pubmed/28881401
http://dx.doi.org/10.1111/imm.12834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765376/
https://www.ncbi.nlm.nih.gov/pubmed/28881401
http://dx.doi.org/10.1111/imm.12834

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