Mass Spectrometric Analysis of Cerebrospinal Fluid Ubiquitin in Alzheimer's Disease and Parkinsonian Disorders

PURPOSE: Dysfunctional proteostasis, with decreased protein degradation and an accumulation of ubiquitin into aggregated protein inclusions, is a feature of neurodegenerative diseases. Identifying new potential biomarkers in cerebrospinal fluid (CSF) reflecting this process could contribute importan...

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Detalles Bibliográficos
Autores principales: Sjödin, Simon, Hansson, Oskar, Öhrfelt, Annika, Brinkmalm, Gunnar, Zetterberg, Henrik, Brinkmalm, Ann, Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765402/
https://www.ncbi.nlm.nih.gov/pubmed/28972305
http://dx.doi.org/10.1002/prca.201700100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765402/
https://www.ncbi.nlm.nih.gov/pubmed/28972305
http://dx.doi.org/10.1002/prca.201700100

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