Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc‐glycosylation

Transient gene expression (TGE) is a methodology employed in bioprocessing for the fast provision of recombinant protein material. Mild hypothermia is often introduced to overcome the low yield typically achieved with TGE and improve specific protein productivity. It is therefore of interest to exam...

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Detalles Bibliográficos
Autores principales: Sou, Si N., Lee, Ken, Nayyar, Kalpana, Polizzi, Karen M., Sellick, Christopher, Kontoravdi, Cleo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
COMMUNICATION TO THE EDITORS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765507/
https://www.ncbi.nlm.nih.gov/pubmed/28921534
http://dx.doi.org/10.1002/bit.26456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765507/
https://www.ncbi.nlm.nih.gov/pubmed/28921534
http://dx.doi.org/10.1002/bit.26456

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