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Exploring cellular behavior under transient gene expression and its impact on mAb productivity and Fc‐glycosylation
Transient gene expression (TGE) is a methodology employed in bioprocessing for the fast provision of recombinant protein material. Mild hypothermia is often introduced to overcome the low yield typically achieved with TGE and improve specific protein productivity. It is therefore of interest to exam...
Autores principales: | Sou, Si N., Lee, Ken, Nayyar, Kalpana, Polizzi, Karen M., Sellick, Christopher, Kontoravdi, Cleo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765507/ https://www.ncbi.nlm.nih.gov/pubmed/28921534 http://dx.doi.org/10.1002/bit.26456 |
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