Cargando…

One pot synthesis of GDP‐mannose by a multi‐enzyme cascade for enzymatic assembly of lipid‐linked oligosaccharides

Glycosylation of proteins is a key function of the biosynthetic‐secretory pathway in the endoplasmic reticulum (ER) and Golgi apparatus. Glycosylated proteins play a crucial role in cell trafficking and signaling, cell‐cell adhesion, blood‐group antigenicity, and immune response. In addition, the gl...

Descripción completa

Detalles Bibliográficos
Autores principales: Rexer, Thomas F.T., Schildbach, Anna, Klapproth, Jan, Schierhorn, Angelika, Mahour, Reza, Pietzsch, Markus, Rapp, Erdmann, Reichl, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765510/
https://www.ncbi.nlm.nih.gov/pubmed/28922469
http://dx.doi.org/10.1002/bit.26454