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One pot synthesis of GDP‐mannose by a multi‐enzyme cascade for enzymatic assembly of lipid‐linked oligosaccharides

Glycosylation of proteins is a key function of the biosynthetic‐secretory pathway in the endoplasmic reticulum (ER) and Golgi apparatus. Glycosylated proteins play a crucial role in cell trafficking and signaling, cell‐cell adhesion, blood‐group antigenicity, and immune response. In addition, the gl...

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Detalles Bibliográficos
Autores principales:	Rexer, Thomas F.T., Schildbach, Anna, Klapproth, Jan, Schierhorn, Angelika, Mahour, Reza, Pietzsch, Markus, Rapp, Erdmann, Reichl, Udo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765510/ https://www.ncbi.nlm.nih.gov/pubmed/28922469 http://dx.doi.org/10.1002/bit.26454

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