Subtle Deregulation of the Wnt‐Signaling Pathway Through Loss of Apc2 Reduces the Fitness of Intestinal Stem Cells

The importance of the Wnt‐signaling pathway on the regulation and maintenance of the intestinal stem cell (ISC) population is well recognized. However, our current knowledge base is founded on models using systems of gross deregulation of the Wnt‐signaling pathway. Given the importance of this signa...

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Detalles Bibliográficos
Autores principales: Young, Madeleine A., Daly, Carl S., Taylor, Elaine, James, Rhiannon, Clarke, Alan Richard, Reed, Karen Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Tissue‐Specific Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765519/
https://www.ncbi.nlm.nih.gov/pubmed/29027285
http://dx.doi.org/10.1002/stem.2712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765519/
https://www.ncbi.nlm.nih.gov/pubmed/29027285
http://dx.doi.org/10.1002/stem.2712

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