Sitagliptin improved glucose assimilation in detriment of fatty-acid utilization in experimental type-II diabetes: role of GLP-1 isoforms in Glut4 receptor trafficking

BACKGROUND: The distribution of glucose and fatty-acid transporters in the heart is crucial for energy consecution and myocardial function. In this sense, the glucagon-like peptide-1 (GLP-1) enhancer, sitagliptin, improves glucose homeostasis but it could also trigger direct cardioprotective actions...

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Detalles Bibliográficos
Autores principales: Ramírez, E., Picatoste, B., González-Bris, A., Oteo, M., Cruz, F., Caro-Vadillo, A., Egido, J., Tuñón, J., Morcillo, M. A., Lorenzo, Ó.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765634/
https://www.ncbi.nlm.nih.gov/pubmed/29325553
http://dx.doi.org/10.1186/s12933-017-0643-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765634/
https://www.ncbi.nlm.nih.gov/pubmed/29325553
http://dx.doi.org/10.1186/s12933-017-0643-2

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