Overexpression of the proneural transcription factor ASCL1 in chronic lymphocytic leukemia with a t(12;14)(q23.2;q32.3)

BACKGROUND: Translocations of the IGH locus on 14q32.3 are present in about 8% of patients with chronic lymphocytic leukemia (CLL) and contribute to leukemogenesis by deregulating the expression of the IGH-partner genes. Identification of these genes and investigation of the downstream effects of th...

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Detalles Bibliográficos
Autores principales: Malli, Theodora, Rammer, Melanie, Haslinger, Sabrina, Burghofer, Jonathan, Burgstaller, Sonja, Boesmueller, Hans-Christian, Marschon, Renate, Kranewitter, Wolfgang, Erdel, Martin, Deutschbauer, Sabine, Webersinke, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765657/
https://www.ncbi.nlm.nih.gov/pubmed/29344090
http://dx.doi.org/10.1186/s13039-018-0355-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765657/
https://www.ncbi.nlm.nih.gov/pubmed/29344090
http://dx.doi.org/10.1186/s13039-018-0355-7

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