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Paracrine and epigenetic control of CAF-induced metastasis: the role of HOTAIR stimulated by TGF-ß1 secretion

BACKGROUND: The communication between carcinoma associated fibroblasts (CAFs) and cancer cells facilitate tumor metastasis. In this study, we further underlying the epigenetic mechanisms of CAFs feed the cancer cells and the molecular mediators involved in these processes. METHODS: MCF-7 and MDA-MB-...

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Detalles Bibliográficos
Autores principales: Ren, Yu, Jia, Huan-huan, Xu, Yi-qi, Zhou, Xuan, Zhao, Xiao-hui, Wang, Yun-fei, Song, Xin, Zhu, Zhi-yan, Sun, Ting, Dou, Yan, Tian, Wei-ping, Zhao, Xiu-lan, Kang, Chun-sheng, Mei, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765658/
https://www.ncbi.nlm.nih.gov/pubmed/29325547
http://dx.doi.org/10.1186/s12943-018-0758-4