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Bone marrow failure may be caused by chromosome anomalies exerting effects on RUNX1T1 gene

BACKGROUND: The majority of the cases of bone marrow failure syndromes/aplastic anaemias (BMFS/AA) are non-hereditary and considered idiopathic (80–85%). The peripheral blood picture is variable, with anaemia, neutropenia and/or thrombocytopenia, and the patients with idiopathic BMFS/AA may have a r...

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Detalles Bibliográficos
Autores principales: Valli, R., Vinti, L., Frattini, A., Fabbri, M., Montalbano, G., Olivieri, C., Minelli, A., Locatelli, F., Pasquali, F., Maserati, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765665/
https://www.ncbi.nlm.nih.gov/pubmed/29344089
http://dx.doi.org/10.1186/s13039-017-0352-2