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A multiple imputation method based on weighted quantile regression models for longitudinal censored biomarker data with missing values at early visits
BACKGROUND: In patient-based studies, biomarker data are often subject to left censoring due to the detection limits, or to incomplete sample or data collection. In the context of longitudinal regression analysis, inappropriate handling of these issues could lead to biased parameter estimates. We de...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765696/ https://www.ncbi.nlm.nih.gov/pubmed/29325529 http://dx.doi.org/10.1186/s12874-017-0463-9 |