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A FCGR3A Polymorphism Predicts Anti-drug Antibodies in Chronic Inflammatory Bowel Disease Patients Treated With Anti-TNF

Background. The production of anti-drug antibodies (ADAs) against IgG monoclonal antibodies (mAbs) targeting tumour necrosis factor (TNF) is an important cause of loss of response to anti-TNF mAbs in patients with inflammatory bowel diseases (IBD) such as Crohn's disease (CD) and ulcerative col...

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Detalles Bibliográficos
Autores principales: Romero-Cara, Patricia, Torres-Moreno, Daniel, Pedregosa, José, Vílchez, Juan Antonio, García-Simón, María Sergia, Ruiz-Merino, Guadalupe, Morán-Sanchez, Senador, Conesa-Zamora, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765734/
https://www.ncbi.nlm.nih.gov/pubmed/29333082
http://dx.doi.org/10.7150/ijms.22812