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Renal-protective effect of thalidomide in streptozotocin-induced diabetic rats through anti-inflammatory pathway

BACKGROUND: Diabetic nephropathy (DN) is a major microvascular complication in diabetes. An increasing body of evidence has shown that DN is related to chronic inflammation, kidney hypertrophy, and fibrosis. While thalidomide has been shown to have anti-inflammatory and antifibrotic effects, the eff...

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Detalles Bibliográficos
Autores principales: Zhang, Hongxia, Yang, Yanlan, Wang, Yanqin, Wang, Baodong, Li, Rongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765978/
https://www.ncbi.nlm.nih.gov/pubmed/29386886
http://dx.doi.org/10.2147/DDDT.S149298