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Lifespan extension without fertility reduction following dietary addition of the autophagy activator Torin1 in Drosophila melanogaster

Autophagy is a highly conserved mechanism for cellular repair that becomes progressively down-regulated during normal ageing. Hence, manipulations that activate autophagy could increase lifespan. Previous reports show that manipulations to the autophagy pathway can result in longevity extension in y...

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Detalles Bibliográficos
Autores principales: Mason, Janet S., Wileman, Tom, Chapman, Tracey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766080/
https://www.ncbi.nlm.nih.gov/pubmed/29329306
http://dx.doi.org/10.1371/journal.pone.0190105