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Lifespan extension without fertility reduction following dietary addition of the autophagy activator Torin1 in Drosophila melanogaster
Autophagy is a highly conserved mechanism for cellular repair that becomes progressively down-regulated during normal ageing. Hence, manipulations that activate autophagy could increase lifespan. Previous reports show that manipulations to the autophagy pathway can result in longevity extension in y...
Autores principales: | Mason, Janet S., Wileman, Tom, Chapman, Tracey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766080/ https://www.ncbi.nlm.nih.gov/pubmed/29329306 http://dx.doi.org/10.1371/journal.pone.0190105 |
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