Erythrocyte Inosine triphosphatase activity: A potential biomarker for adverse events during combination antiretroviral therapy for HIV

The purine analogues tenofovir and abacavir are precursors of potential substrates for the enzyme Inosine 5’-triphosphate pyrophosphohydrolase (ITPase). Here, we investigated the association of ITPase activity and ITPA genotype with the occurrence of adverse events (AEs) during combination antiretro...

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Detalles Bibliográficos
Autores principales: Peltenburg, N. Chantal, Bierau, Jörgen, Bakker, Jaap A., Schippers, Jolanda A., Lowe, Selwyn H., Paulussen, Aimée D. C., van den Bosch, Bianca J. C., Leers, Mathie P. G., Hansen, Bettina E., Verbon, Annelies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766130/
https://www.ncbi.nlm.nih.gov/pubmed/29329318
http://dx.doi.org/10.1371/journal.pone.0191069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766130/
https://www.ncbi.nlm.nih.gov/pubmed/29329318
http://dx.doi.org/10.1371/journal.pone.0191069

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