EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients

BACKGROUND & AIMS: Inhibitors of the epidermal growth factor receptor (EGFR) are the first-line therapy for patients with metastatic colorectal tumors without RAS mutations. However, EGFR inhibitors are ineffective in these patients, and tumor level of EGFR does not associate with response to th...

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Detalles Bibliográficos
Autores principales: Srivatsa, Sriram, Paul, Mariel C., Cardone, Claudia, Holcmann, Martin, Amberg, Nicole, Pathria, Paulina, Diamanti, Michaela A., Linder, Markus, Timelthaler, Gerald, Dienes, Hans P., Kenner, Lukas, Wrba, Fritz, Prager, Gerald W., Rose-John, Stefan, Eferl, Robert, Liguori, Giuseppina, Botti, Gerardo, Martinelli, Erika, Greten, Florian R., Ciardiello, Fortunato, Sibilia, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766132/
https://www.ncbi.nlm.nih.gov/pubmed/28400195
http://dx.doi.org/10.1053/j.gastro.2017.03.053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766132/
https://www.ncbi.nlm.nih.gov/pubmed/28400195
http://dx.doi.org/10.1053/j.gastro.2017.03.053

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