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Immunization with gingipain A hemagglutinin domain of Porphyromonas gingivalis induces IgM antibodies binding to malondialdehyde-acetaldehyde modified low-density lipoprotein

Treatment of periodontitis has beneficial effects on systemic inflammation markers that relate to progression of atherosclerosis. We aimed to investigate whether immunization with A hemagglutinin domain (Rgp44) of Porphyromonas gingivalis (Pg), a major etiologic agent of periodontitis, would lead to...

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Detalles Bibliográficos
Autores principales: Kyrklund, Mikael, Kummu, Outi, Kankaanpää, Jari, Akhi, Ramin, Nissinen, Antti, Turunen, S. Pauliina, Pussinen, Pirkko, Wang, Chunguang, Hörkkö, Sohvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766137/
https://www.ncbi.nlm.nih.gov/pubmed/29329335
http://dx.doi.org/10.1371/journal.pone.0191216