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Atypical E2f functions are critical for pancreas polyploidization

The presence of polyploid cells in the endocrine and exocrine pancreas has been reported for four decades. In rodents, pancreatic polyploidization is initiated after weaning and the number of polyploid cells increases with age. Surprisingly the molecular regulators and biological functions of polypl...

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Detalles Bibliográficos
Autores principales: Matondo, Ramadhan B., Moreno, Eva, Toussaint, Mathilda J. M., Tooten, Peter C. J., van Essen, Saskia C., van Liere, Elsbeth A., Youssef, Sameh A., Bongiovanni, Laura, de Bruin, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766144/
https://www.ncbi.nlm.nih.gov/pubmed/29329320
http://dx.doi.org/10.1371/journal.pone.0190899