A novel non-canonical PIP-box mediates PARG interaction with PCNA

Poly(ADP-ribose) glycohydrolase (PARG) regulates cellular poly(ADP-ribose) (PAR) levels by rapidly cleaving glycosidic bonds between ADP-ribose units. PARG interacts with proliferating cell nuclear antigen (PCNA) and is strongly recruited to DNA damage sites in a PAR- and PCNA-dependent fashion. Her...

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Detalles Bibliográficos
Autores principales: Kaufmann, Tanja, Grishkovskaya, Irina, Polyansky, Anton A., Kostrhon, Sebastian, Kukolj, Eva, Olek, Karin M., Herbert, Sebastien, Beltzung, Etienne, Mechtler, Karl, Peterbauer, Thomas, Gotzmann, Josef, Zhang, Lijuan, Hartl, Markus, Zagrovic, Bojan, Elsayad, Kareem, Djinovic-Carugo, Kristina, Slade, Dea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766153/
https://www.ncbi.nlm.nih.gov/pubmed/28934471
http://dx.doi.org/10.1093/nar/gkx604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766153/
https://www.ncbi.nlm.nih.gov/pubmed/28934471
http://dx.doi.org/10.1093/nar/gkx604

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