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ALYREF mainly binds to the 5′ and the 3′ regions of the mRNA in vivo

The TREX complex (TREX) plays key roles in nuclear export of mRNAs. However, little is known about its transcriptome-wide binding targets. We used individual cross-linking and immunoprecipitation (iCLIP) to identify the binding sites of ALYREF, an mRNA export adaptor in TREX, in human cells. Consist...

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Detalles Bibliográficos
Autores principales: Shi, Min, Zhang, Heng, Wu, Xudong, He, Zhisong, Wang, Lantian, Yin, Shanye, Tian, Bin, Li, Guohui, Cheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766156/
https://www.ncbi.nlm.nih.gov/pubmed/28934468
http://dx.doi.org/10.1093/nar/gkx597