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A novel requirement for DROSHA in maintenance of mammalian CG methylation

In mammals, faithful inheritance of genomic methylation patterns ensures proper gene regulation and cell behaviour, impacting normal development and fertility. Following establishment, genomic methylation patterns are transmitted through S-phase by the maintenance methyltransferase Dnmt1. Using a pr...

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Detalles Bibliográficos
Autores principales: Stathopoulou, Athanasia, Chhetri, Jyoti B., Ambrose, John C., Estève, Pierre-Olivier, Ji, Lexiang, Erdjument-Bromage, Hediye, Zhang, Guoqiang, Neubert, Thomas A., Pradhan, Sriharsa, Herrero, Javier, Schmitz, Robert J., Ooi, Steen K.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766157/
https://www.ncbi.nlm.nih.gov/pubmed/28934503
http://dx.doi.org/10.1093/nar/gkx695