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STN1–POLA2 interaction provides a basis for primase-pol α stimulation by human STN1

The CST (CTC1–STN1–TEN1) complex mediates critical functions in maintaining telomere DNA and overcoming genome-wide replication stress. A conserved biochemical function of the CST complex is its primase-Pol α (PP) stimulatory activity. In this report, we demonstrate the ability of purified human STN...

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Detalles Bibliográficos
Autores principales: Ganduri, Swapna, Lue, Neal F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766158/
https://www.ncbi.nlm.nih.gov/pubmed/28934486
http://dx.doi.org/10.1093/nar/gkx621