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STN1–POLA2 interaction provides a basis for primase-pol α stimulation by human STN1
The CST (CTC1–STN1–TEN1) complex mediates critical functions in maintaining telomere DNA and overcoming genome-wide replication stress. A conserved biochemical function of the CST complex is its primase-Pol α (PP) stimulatory activity. In this report, we demonstrate the ability of purified human STN...
Autores principales: | Ganduri, Swapna, Lue, Neal F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766158/ https://www.ncbi.nlm.nih.gov/pubmed/28934486 http://dx.doi.org/10.1093/nar/gkx621 |
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