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Combining asymmetric (13)C-labeling and isotopic filter/edit NOESY: a novel strategy for rapid and logical RNA resonance assignment
Although ∼98% of the human genomic output is transcribed as non-protein coding RNA, <2% of the protein data bank structures comprise RNA. This huge structural disparity stems from combined difficulties of crystallizing RNA for X-ray crystallography along with extensive chemical shift overlap and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766159/ https://www.ncbi.nlm.nih.gov/pubmed/28934505 http://dx.doi.org/10.1093/nar/gkx591 |