Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans

DNA interstrand crosslinks (ICLs) are generated by endogenous sources and chemotherapeutics, and pose a threat to genome stability and cell survival. Using Caenorhabditis elegans mutants, we identify DNA repair factors that protect against the genotoxicity of ICLs generated by trioxsalen/ultraviolet...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilson, David M., Rieckher, Matthias, Williams, Ashley B., Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766164/
https://www.ncbi.nlm.nih.gov/pubmed/28934497
http://dx.doi.org/10.1093/nar/gkx660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766164/
https://www.ncbi.nlm.nih.gov/pubmed/28934497
http://dx.doi.org/10.1093/nar/gkx660

Ejemplares similares