In vivo probing of nascent RNA structures reveals principles of cotranscriptional folding

Defining the in vivo folding pathway of cellular RNAs is essential to understand how they reach their final native conformation. We here introduce a novel method, named Structural Probing of Elongating Transcripts (SPET-seq), that permits single-base resolution analysis of transcription intermediate...

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Detalles Bibliográficos
Autores principales: Incarnato, Danny, Morandi, Edoardo, Anselmi, Francesca, Simon, Lisa M., Basile, Giulia, Oliviero, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766169/
https://www.ncbi.nlm.nih.gov/pubmed/28934475
http://dx.doi.org/10.1093/nar/gkx617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766169/
https://www.ncbi.nlm.nih.gov/pubmed/28934475
http://dx.doi.org/10.1093/nar/gkx617

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