A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into mesoderm

Targeted differentiation of human induced pluripotent stem cells (hiPSCs) using only chemicals would have value-added clinical potential in the regeneration of complex cell types including cardiomyocytes. Despite the availability of several chemical inhibitors targeting proteins involved in signalin...

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Detalles Bibliográficos
Autores principales: Taniguchi, Junichi, Pandian, Ganesh N., Hidaka, Takuya, Hashiya, Kaori, Bando, Toshikazu, Kim, Kyeong Kyu, Sugiyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766170/
https://www.ncbi.nlm.nih.gov/pubmed/28934500
http://dx.doi.org/10.1093/nar/gkx693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766170/
https://www.ncbi.nlm.nih.gov/pubmed/28934500
http://dx.doi.org/10.1093/nar/gkx693

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