Blocking the RecA activity and SOS-response in bacteria with a short α-helical peptide

The RecX protein, a very active natural RecA protein inhibitor, can completely disassemble RecA filaments at nanomolar concentrations that are two to three orders of magnitude lower than that of RecA protein. Based on the structure of RecX protein complex with the presynaptic RecA filament, we desig...

Descripción completa

Detalles Bibliográficos
Autores principales: Yakimov, Alexander, Pobegalov, Georgii, Bakhlanova, Irina, Khodorkovskii, Mikhail, Petukhov, Michael, Baitin, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Synthetic Biology and Bioengineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766188/
https://www.ncbi.nlm.nih.gov/pubmed/28934502
http://dx.doi.org/10.1093/nar/gkx687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766188/
https://www.ncbi.nlm.nih.gov/pubmed/28934502
http://dx.doi.org/10.1093/nar/gkx687

Ejemplares similares