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Blocking the RecA activity and SOS-response in bacteria with a short α-helical peptide
The RecX protein, a very active natural RecA protein inhibitor, can completely disassemble RecA filaments at nanomolar concentrations that are two to three orders of magnitude lower than that of RecA protein. Based on the structure of RecX protein complex with the presynaptic RecA filament, we desig...
Autores principales: | Yakimov, Alexander, Pobegalov, Georgii, Bakhlanova, Irina, Khodorkovskii, Mikhail, Petukhov, Michael, Baitin, Dmitry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766188/ https://www.ncbi.nlm.nih.gov/pubmed/28934502 http://dx.doi.org/10.1093/nar/gkx687 |
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