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Number of inadvertent RNA targets for morpholino knockdown in Danio rerio is largely underestimated: evidence from the study of Ser/Arg-rich splicing factors

Although the involvement of Ser/Arg-rich (SR) proteins in RNA metabolism is well documented, their role in vertebrate development remains elusive. We, therefore, elected to take advantage of the zebrafish model organism to study the SR genes' functions using the splicing morpholino (sMO) microi...

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Detalles Bibliográficos
Autores principales: Joris, Marine, Schloesser, Marie, Baurain, Denis, Hanikenne, Marc, Muller, Marc, Motte, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766196/
https://www.ncbi.nlm.nih.gov/pubmed/28934490
http://dx.doi.org/10.1093/nar/gkx638